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Cerebral Embolism Task Force

Arch Neurol. 1986;43(1):71-84.

Abstract
• One in six ischemic strokes is due to cardiogenic embolism. The current knowledge about the natural history, diagnosis, prevention, and treatment of cardioembolic stroke is reviewed. Nonrheumatic atrial fibrillation is the most frequent substrate for brain embolism; patients with this dysrhythmia have a fivefold increase in the risk of stroke. Ischemic heart disease (25%), rheumatic mitral stenosis (10%), and prosthetic cardiac valves (10%) are other major sources of cardioembolic stroke. Mitral annulus calcification and calcific aortic stenosis infrequently serve as cardioembolic sources. As cardiac sources of embolic stroke are often identifiable prior to stroke, many of these strokes are potentially preventable.

Footnotes
Accepted for publication Feb 12, 1985.

Cerebral Embolism Task Force members are as follows (alphabetically): Mark L. Dyken, MD, Indiana University Medical School, Indianapolis; Marc Fisher, MD, Department of Neurology, Worcester (Mass) Memorial Hospital; M. J. G. Harrison, MD, Department of Neurology, Middlesex Hospital, London; and Robert G. Hart, MD, and David G. Sherman, MD, Department of Medicine, University of Texas Health Science Center, San Antonio.

Read before the Task Force of the American College of Chest Physicians and National Heart, Lung, and Blood Institute Conference on Antithrombotic Therapy, Chicago, Sept 21, 1984.

Reprint requests to Department of Medicine, University of Texas Health Science Center, 7703 Floyd Curl Dr, San Antonio, TX 78284 (Dr Hart).

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